Help give People hope for better days

$22,481 of $25,000 raised


Despite being one of the most prevalent diseases in the world, migraine research is severely underfunded. It's our mission to change that.
NIH funding for migraine research is less than 2% of federal funding for neurodegenerative diseases and less than 1% of funding for chronic diseases. The Association of Migraine Disorders is proud to be another source of funding for investigators who are committed to advancing migraine research.
Research opens the door to better treatments and improved care for people with migraine. While there have been some groundbreaking strides in treatment developments over the past couple of years, the sad reality is that there are still millions of people who have yet to get their lives back from this debilitating and invisible disease. More research is critical to finding effective and tolerable treatments for ALL people living with migraine.
Patients’ Role in Accelerating Research (1)

A Patient's Role in Accelerating Research (Webinar)

Did you know that you could play a role in the next big migraine research development? The truth is, many new medical developments wouldn't be possible without patients! Don't miss this webinar about what role patients' play in research and to learn what participation looks like.

My Migraine Story: From Fear to Freedom

A woman shares her experience participating in a clinical trial for an investigational acute migraine treatment. Her participation gave her hope for "a life without the constant fear of my migraine disease dragging [her] down."

Our Research Initiative

The Association of Migraine Disorders research initiative is led by a Research Advisory Committee consisting of 20 brilliant, leading researchers and medical professionals who help identify knowledge gaps in migraine to influence future research projects. We are excited to share that two projects have been approved and funded so far this year and there are several additional projects under review. We hope to fund 3 additional projects by the end of the year, but we need your help!

2021 Approved Research

William Renthal, MD, PhD
William Renthal, MD, PhD

Director of Headache Research
Assistant Professor of Neurology
Brigham and Women’s Hospital and Harvard Medical School

Project: Characterization of Migraine Characteristics and Treatment Response Using Semantic Learning

Summary: This project will develop a program that will allow researchers to rapidly scan through thousands of medical records to identify the various forms of migraine and how they respond to treatments in order to help physicians personalize migraine treatment.  

Dr. Renthal’s response to "How will your research lead to a better understanding of migraine conditions?" 

"We aim to build a tool that will allow rapid extraction of migraine patients from electronic medical records and their associated symptoms and treatment response, allowing us to study these more homogenous cohorts. Specifically, we aim to understand genetic differences that may drive treatment response to CGRP monoclonal antibodies."

Status: Funded

Project: Understanding the Association Between Sleep Apnea and Migraine

Collaborators and Advisors:

Carl Saab, PhD - Director, Pain Science Technology and Research Lab, Lerner Research Institute, Cleveland Clinic Lerner College of Medicine

Reena Mehra, MD, MS - Staff Physician and Professor of Medicine of the Cleveland Clinic Lerner College of Medicine, Cleveland Clinic Lerner College of Medicine

Summary: This project aims to investigate if sleep apnea and migraine are associated conditions and address whether treating sleep apnea will improve migraine frequency and symptoms. 

Dr. Gruenthal’s response to "How will your research lead to a better understanding of migraine conditions?" 

"The project will foster a more detailed understanding of the causal nature between sleep disorders (especially sleep-disordered breathing, such as obstructive sleep apnea) and migraine, and address the question of whether proven therapies for sleep-disordered breathing (specifically positive airway pressure) also improve migraine outcomes, such as migraine frequency and intensity."

Status: Approved by Research Advisory Committee, Awaiting Funding

Gruenthal Photo
Eric Gruenthal, MD

Sleep Medicine Fellow
Cleveland Clinic Foundation
Cleveland Clinic Lerner College of Medicine

“More funding would attract new researchers to the field, because they would see it as an emerging space to grow. Bringing in new ideas and approaches would significantly advance migraine research and ultimately patient care.”

-Amynah Pradhan, PhD, AMD Research Advisory Committee Member

Help us fund three more projects by the end of the year! Other projects under consideration include:

  • Understanding how hormones affect the nervous system
  • A longitudinal patient registry
  • Identifying when migraine affects dizziness
  • The role of biomarkers and genetics


AMD has given over $600,000 to migraine research, but there’s more work left to be done


Match to clinical trials in 60 seconds with Antidote

More than 80% of medical research is delayed due to a lack of participants.

Antidote is a tool that helps accelerate new medical research by connecting patients to currently recruiting clinical trials. By filling out a quick questionnaire, you will be paired with clinical trials you may be eligible for.

Spread The Word

Help raise awareness about the #ResearchIsHope fundraising campaign by sharing the images and sample text below on social media

Join me in supporting @migrainedisordr’s #ResearchIsHope campaign to raise funds for innovative migraine research. No donation is too small!

Donate at

#givingtuesday #migraineresearch

As you may know, I have lived with migraine for [blank years]. It has impacted my life in so many ways. I am excited to share that @migrainedisorders is restoring my hope for better days with their #ResearchIsHope campaign to stimulate innovative migraine research.

They have already supported two research projects this year and hope to fund three more by the end of the year, but they need our help!

Donate at

#givingtuesday #migraineresearch

Your donation goes even further! All donations made in November will be doubled up to $5,000 by cove. All donations made in December will be doubled up to $10,000 by a generous anonymous donor. No donation is too small!

Giving Grid

Want to give to an initiative beyond research? Help us fill up the grid! See what each donation amount can help AMD get! Plus, you can upload your picture to help us make a collage of donors. Don't forget to share!

Donate Using the gift swap

This year, thanks to numerous generous product donors, we are excited to share our Mystery Gift fundraising initiative! The Mystery Gift Fundraiser allows you to receive a gift with your donation of $25, $50, $100 or $250.

Donate By Check

If you prefer to write a check, please make it payable to the “Association of Migraine Disorders” and mail to:

Association of Migraine Disorders
PO Box 870
North Kingstown, RI 02852

Donate Stocks

Contact us at [email protected] for instructions on how to donate stocks.

Donate With Cryptocurrency

Can’t donate? Start a fundraiser

Harness the support of your friends and family by starting your own Facebook fundraiser for the #ResearchIsHope campaign.

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