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Migraine Research Initiative

The Association of Migraine Disorders is devoted to accelerating the most promising area of neuroscience research: migraine. AMD’s Migraine Research Initiative is led by AMD’s research committee consisting of brilliant, leading researchers who help identify knowledge gaps in migraine to influence future research projects. AMD provides funding for innovative research projects through its grant program. Finally, AMD strives to form an inter-institutional and multi-disciplinary network of migraine researchers and medical professionals through its resource hub and communication platform, the Migraine Science Collaborative.

Grant Program

We believe our grant programs create a consistent effort to support the early careers of researchers with an interest in migraine disease. Our nonprofit organization resembles the role of venture capital organizations that nurture start-up companies.

AMD has developed a comprehensive program that helps not only to fund specific research projects, but also to launch the careers of those willing to specialize in migraine research. We offer programs to introduce students into this area of neuroscience, through shadowing programs, travel grants, small introductory grants and then support more experienced researchers to explore new ideas with intermediate-sized grants, managed by the Migraine Research Foundation.

Our expectation is that the best of these ideas will be ready to apply to much larger grants, such as those offered by NIH. The most unique aspect of our program is our support of interdisciplinary migraine-related research at the Brown Institute for Brain Science and the funding of a post-doctoral fellowship in migraine research.

The Carney Institute for Brain Science Post Doctoral Research Position

This unique program funds an opportunity for a graduate student to launch their career in migraine research at the Brown Institute for Brain Science.

First recipient: Tyler Clark Brown, PhD

Second recipient: Bruno Pradier, PhD

Incubator Grants

The Migraine Research Foundation (MRF) and the Association of Migraine Disorders (AMD) announce the opening of a joint Request for Proposals for migraine research grants. The application deadline is at the end of July each year.

MRF is committed to discovering the causes, improving the treatments, and finding a cure, and AMD stimulates increased research in the area of migraine disorders.

We seek projects that will help sufferers by advancing our ability to understand and treat migraine. As a result, we offer seed-money grants for projects that are important, achievable, and innovative that will ultimately lead to better treatment and quality of life for sufferers of migraine and migraine disorders.

While we welcome all proposals relevant to basic or clinical migraine research, we are particularly interested in translational projects and those related to migraine variants, the relationship between concussions and migraines, post-traumatic headaches and migraine, hormonal effects on the nervous system, effects of nutrition on migraine, and other migraine variants, such as vestibular migraine and sinus migraine. Projects should take an original approach to the subject and have the potential to move the field forward in a significant way.

Please be advised that due to the large number of grant requests we receive, applications must follow the required format and conform to the guidelines to be considered.

Visit the grant page at the Migraine Research Foundation’s website to see details and the application.

Grants awarded to:

2016-17 Lyn Griffiths, Ph.D.

2017-18 Suzanne Bertisch, MD

2018-19 Patricia Pozo-Rosich, Ph.D.

Resident Research Grant

The program offers one-year grants to any Residents conducting a research project that is related to improving our understanding of migraine variants. The Resident Research Grants are available at any time.

We are using CORE to administer our Resident Research Grants. You can follow this link to see more info and to apply for a grant.

Research Funded By AMD

2020

CORE Grant – $10,000

Project: Clinical Utility of Multifrequency VEMP in Vestibular Migraine Diagnosis

Principal Investigator: Janet Choi, USC


2019

MRF Grant – $48,000

Project: Genetic analysis of mitochondrial DNA and nuclear-encoded mitochondrial genes in familial migraine with aura

Principal Investigator: Lyn Griffiths Ph.D., Queensland University of Technology

 

CORE Grant – $10,000

Project: Mindfulness-Based Stress Reduction for the Treatment of Vestibular Migraine

Principal Investigator: Eric Formeister, UC SF


2017

MRF Grant – $50,000

Project: Shedding Light on Migraine: Exploring Novel Light Metrics as a Trigger of Migraine

Principal Investigator: Suzanne Bertisch, Beth Israel Deaconess Medical Center to Brigham & Women’s Hospital

UPDATE: Completed in 2020 https://migraineresearchfoundation.org/researchers/suzanne-bertisch/

 

CORE Grant – $5,500

Project: Randomized clinical trial of nortriptyline in treatment of vestibular migraine

Principal Investigator: Hossein Mahboubi, UC Irvine

UPDATE: Research ended due to lack of participants


2016

MRF Grant – $50,000

Project: Microglial proliferation in women with menstrual migraines

Principal Investigator: Clas Linnman, Boston Children’s Hospital


2015

MRF Grant – $50,000

Project: microMIG: searching for new biomarkers in migraine using microRNA expression profile analysis

Principal Investigator: Patricia Vall, Pozo-Rosich, d’Hebron University Hospital


2014

Direct Grant – $190,000

Project: Patterns of Migraine Disease in Otolaryngology: A CHEER Network Study

Principal Investigator: David Witsell, MD, MHS, Duke University

 

MRF Grant – $50,000

Project: Gastroparesis in Monogenic Migraine Mouse Models

Principal Investigator: Robert Shapiro, UVM

 

MRF Grant – $50,000

Project: Use of Next Generation Sequencing Technology to Identify Novel Hemiplegic Migraine and Migraine Related Mutations.

Principal Investigator: Lyn Griffiths Ph.D., Queensland University of Technology

 

Direct Grant – $50,000

Project: The Role of Metabotropic Glutamate Receptors in Migraine

Principal Investigator: Maggie Waung, University of California San Francisco

 

Direct Grant – $50,000

Project: A prospective randomized cross-over trial of nortriptyline and topiramate in the initial treatment of vestibular migraine

Principal Investigator: Anthony Mikulec, MD, Saint Louis University

Migraine Science Collaborative

The Migraine Science Collaborative is a membership-based, targeted resource hub and communication platform.  It was founded, and is supported, by the Association of Migraine Disorders.

Mission Statement

The Migraine Science Collaborative strives to form an inter-institutional and multi-disciplinary network of migraine researchers and medical professionals in an effort to increase and enhance research in the fields of migraine, cluster and headache disease.

GOALS

  • Unite the migraine, cluster and headache scientific communities through a communication system
  • Support the careers of young investigators through educational resources and a mentorship program
  • Provide bidirectional exchange of guidance, ideas and questions within and between the researchers and medical care providers
  • Encourage increased coordination of research between related or comorbid diseases
  • Create a collaborative environment to help stimulate unique research projects
  • Share funding opportunities, improve grantsmanship and prepare researchers for more successful research funding
  • Attract non-migraine researchers to the migraine community
  • Promote translational research

Meeting of the Minds

The Migraine Science Collaborative’s first Meeting of the Minds focused on Vestibular Migraine. Held, October 4, 2020, the meeting brought together almost 30 professionals with a common interest in vestibular migraine research. Attendees heard about recent research projects, broke into working groups and began discussions on identifying knowledge gaps and creating one or more collaborative research projects in three key areas – pathophysiology, diagnostic testing and therapeutic advances.

  • Alaina Bassett, PhD, AuD
  • Amy Poremba, PhD
  • Mehdi Abouzari, PhD
  • Anne Luebke, PhD
  • Maurizio Versino
  • Jeffery Kuhn, MD
  • Amarylis Velez, PhD
  • Natalia Marangoni, PhD
  • Michael Teixido, MD
  • Amir Kheradmand, MD
  • Monica Mallampalli, PhD
  • Ashley Zaleski-King, AuD
  • James Buskirk, PT
  • Matthew Crowson, MD
  • Claire Ceriani, MD
  • Jacki Rorabaugh, PhD
  • Habib Rizk, MD
  • Marco Mandala, MD, PhD
  • Hamid Djalilian, MD
  • Andrea Hinds, PhD
  • Lori Ginoza, DPT
  • Roberto Teggi, MD
  • Michelle Inserra, MD
  • Magdalena Nowaczewska, MD
  • Joel Goebel, MD
  • Uday Jodhpurkar
  • Eric Liebler
  • Scott Yuan, MD, PhD
  • Shin Beh, MD
  • Stephen Silberstein, MD
  • Rick Godley, MD

Research Advisory Committee

KC Brennan, MD, PhD

University of Utah

Basic mechanisms of migraine and post-traumatic headache

Larry Charleston IV, MD, MSc

University of Michigan

Headache Disorders

Paul Durham, PhD

Missouri State University

Cellular and molecular mechanisms, epigenetics

Gregory Dussor, PhD

University of Texas at Dallas

Pathological mechanisms and therapeutic targets for migraine headache.

Deborah Friedman, MD, MPH, FAAN

University of Texas Southwestern Medical Center

Headache disorders and intracranial pressure disorders

Georgia Hodes, PhD

Virginia Polytechnic Institute and State University

Sex differences in the peripheral and central immune system 

Amanda Jaimeson, PhD

Brown University

Immunology

Felicia Jefferson, PhD

Fort Valley State University

Sleep science and minority research career development

Shivang Joshi, MD, MPH, RPh

DENT Neurologic Institute

Research Focus: Headache disorders

Deena Kuruvilla, MD

Yale School of Medicine

Research Focus: Headache disorders

Dan Levy, PhD

Beth Israel Deaconess Medical Centre & Harvard Medical School

Research Focus: Intracranial meninges and its trigeminal sensory innervation

Nasim Maleki, PhD

Massachusetts General Hospital

Research Focus: Sex-related contributions to migraine disease

Angela O'Neal, MD

Brigham and Women's Hospital

Research Focus: Women's neurology

Jelena Pavlović, MD, PhD

Albert Einstein College of Medicine

Research Focus: Hormonal regulation of migraine

Amynah Pradhan, PhD

Amynah Pradhan, PhD

University of Illinois

Research Focus: Translationally significant animal models of headache 

Carl Saab, MD

Brown University Warren Alpert Medical School & Rhode Island Hospital

Research Focus: Translational research in chronic pain

Stephen Silberstein, MD, FACP, FAAN, FAHS

Thomas Jefferson University

Research Focus: Headache disorders

Rashmi Halker Singh, MD FAHS FAAN

Mayo Clinic

Research Focus: Headache disorders and intracranial pressure disorders

William R. Renthal, MD, PhD

Brigham and Women’s Hospital & Harvard Medical School

Research Focus: Human genetics related to migraine pathophysiology

Gretchen Tietjen, MD

University of Toledo

Research Focus: Migraine, stroke, early life stress, vascular biology

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