Migraine Research Initiative

Accelerating Migraine Research

The Association of Migraine Disorders is devoted to accelerating the most promising area of neuroscience research: migraine.

AMD’s Migraine Research Initiative is led by AMD’s research committee consisting of brilliant, leading researchers who help identify knowledge gaps in migraine to influence future research projects. AMD provides funding for innovative research projects through its grant program. Finally, AMD strives to form an inter-institutional and multi-disciplinary network of migraine researchers and medical professionals through its resource hub and communication platform, the Migraine Science Collaborative.

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Migraine Science Collaborative

The Migraine Science Collaborative is an international resource hub and communication platform designed to facilitate inter-institutional and multi-disciplinary networking for researchers and medical professionals.

The MSC has a goal of accelerating research advances in migraine, cluster and headache diseases.

The MSC platform includes discussion forums, a resource library, an events page, and grant opportunities. A mentor program is in development.

WHO SHOULD BE A MEMBER: Primarily students, residents, postdoctoral fellows, researchers, scientists and clinicians of all specialties and backgrounds. We also welcome pharmaceutical medical liaisons, medical writers and educators.
Your participation in MSC will build a broader and stronger collaboration between all of these currently independent fields and help us advance migraine research for better treatments and cure.

We welcome scientists at all stages of their careers to become members.  It is easy and free of charge. Simply visit the MSC homepage and submit your request for membership.

AMD’s Migraine Research Initiative is led by AMD’s research committee consisting of brilliant, leading researchers who help identify knowledge gaps in migraine to influence future research projects. AMD provides funding for innovative research projects through its grant program. Finally, AMD strives to form an inter-institutional and multi-disciplinary network of migraine researchers and medical professionals through its resource hub and communication platform, the Migraine Science Collaborative.

Research Advisory Committee

KC Brennan, MD, PhD

KC Brennan, MD, PhD

University of Utah

Basic mechanisms of migraine and post-traumatic headache

Larry Charleston IV, MD, MSc

Larry Charleston IV, MD, MSc

University of Michigan

Headache Disorders

Paul Durham, PhD

Paul Durham, PhD

Missouri State University

Cellular and molecular mechanisms, epigenetics

Gregory Dussor, PhD

Gregory Dussor, PhD

University of Texas at Dallas

Pathological mechanisms and therapeutic targets for migraine headache.

Georgia Hodes, PhD

Georgia Hodes, PhD

Virginia Polytechnic Institute and State University

Sex differences in the peripheral and central immune system 

Amanda Jaimeson, PhD

Amanda Jaimeson, PhD

Brown University

Immunology

Felicia Jefferson, PhD

Felicia Jefferson, PhD

Fort Valley State University

Sleep science and minority research career development

Shivang G. Joshi, MD

Shivang Joshi, MD, MPH, RPh

DENT Neurologic Institute

Research Focus: Headache disorders

Deena Kuruvilla, MD

Deena Kuruvilla, MD

Yale School of Medicine

Research Focus: Headache disorders

Dan Levy, PhD

Dan Levy, PhD

Beth Israel Deaconess Medical Centre & Harvard Medical School

Research Focus: Intracranial meninges and its trigeminal sensory innervation

Nasim Maleki, PhD

Nasim Maleki, PhD

Massachusetts General Hospital

Research Focus: Sex-related contributions to migraine disease

Angela O'Neal, MD

Angela O'Neal, MD

Brigham and Women's Hospital

Research Focus: Women’s neurology

Jelena Pavlović, MD, Ph

Jelena Pavlović, MD, PhD

Albert Einstein College of Medicine

Research Focus: Hormonal regulation of migraine

Amynah Pradhan, PhD

Amynah Pradhan, PhD

University of Illinois

Research Focus: Translationally significant animal models of headache 

William Renthal, MD, PhD

William Renthal, MD, PhD

Brigham and Women’s Hospital & Harvard Medical School

Research Focus: Human genetics related to migraine pathophysiology

Carl Saab, PhD

Carl Saab, PhD

Cleveland Clinic

Research Focus: Translational research in chronic pain

Stephen Silberstein, MD, FACP, FAAN, FAHS

Stephen Silberstein, MD, FACP, FAAN, FAHS

Thomas Jefferson University

Research Focus: Headache disorders

Gretchen Tietjen, MD

Gretchen Tietjen, MD

University of Toledo

Research Focus: Migraine, stroke, early life stress, vascular biology

Grant Program

We believe our grant programs create a consistent effort to support the early careers of researchers with an interest in migraine disease. Our nonprofit organization resembles the role of venture capital organizations that nurture start-up companies.

AMD has developed a comprehensive program that helps not only to fund specific research projects, but also to launch the careers of those willing to specialize in migraine research. We offer programs to introduce students into this area of neuroscience, through shadowing programs, travel grants, small introductory grants and then support more experienced researchers to explore new ideas with intermediate-sized grants, managed by the Migraine Research Foundation.

Our expectation is that the best of these ideas will be ready to apply to much larger grants, such as those offered by NIH. The most unique aspect of our program is our support of interdisciplinary migraine-related research at the Brown Institute for Brain Science and the funding of a post-doctoral fellowship in migraine research.

Incubator Grants

The Migraine Research Foundation (MRF) and the Association of Migraine Disorders (AMD) announce the opening of a joint Request for Proposals for migraine research grants. The application deadline is at the end of July each year.

MRF is committed to discovering the causes, improving the treatments, and finding a cure, and AMD stimulates increased research in the area of migraine disorders.

We seek projects that will help sufferers by advancing our ability to understand and treat migraine. As a result, we offer seed-money grants for projects that are important, achievable, and innovative that will ultimately lead to better treatment and quality of life for sufferers of migraine and migraine disorders.

While we welcome all proposals relevant to basic or clinical migraine research, we are particularly interested in translational projects and those related to migraine variants, the relationship between concussions and migraines, post-traumatic headaches and migraine, hormonal effects on the nervous system, effects of nutrition on migraine, and other migraine variants, such as vestibular migraine and sinus migraine. Projects should take an original approach to the subject and have the potential to move the field forward in a significant way.

Please be advised that due to the large number of grant requests we receive, applications must follow the required format and conform to the guidelines to be considered.

Grants awarded to:

The Carney Institute for Brain Science Post Doctoral Research Position

This unique program funds an opportunity for a graduate student to launch their career in migraine research at the Brown Institute for Brain Science.

  • First recipient: Tyler Clark Brown, PhD
  • Second recipient: Bruno Pradier, PhD

Resident Research Grant

The program offers one-year grants to any otolaryngology residents conducting a research project that is related to improving our understanding of migraine variants. The Resident Research Grants are available at any time.

We are using CORE to administer our Resident Research Grants. You can follow this link to see more info and to apply for a grant.

Research Funded By AMD

2020

CORE Grant – $10,000

  • Project: Clinical Utility of Multifrequency VEMP in Vestibular Migraine Diagnosis
  • Principal Investigator: Janet Choi, USC

2019

MRF Grant – $48,000

  • Project: Genetic analysis of mitochondrial DNA and nuclear-encoded mitochondrial genes in familial migraine with aura
  • Principal Investigator: Lyn Griffiths Ph.D., Queensland University of Technology

CORE Grant – $10,000

  • Project: Mindfulness-Based Stress Reduction for the Treatment of Vestibular Migraine
  • Principal Investigator: Eric Formeister, UC SF

2017

MRF Grant – $50,000

CORE Grant – $5,500

  • Project: Randomized clinical trial of nortriptyline in treatment of vestibular migraine
  • Principal Investigator: Hossein Mahboubi, UC Irvine
  • UPDATE: Research ended due to lack of participants

2016

MRF Grant – $50,000

  • Project: Microglial proliferation in women with menstrual migraines
  • Principal Investigator: Clas Linnman, Boston Children’s Hospital

2015

MRF Grant – $50,000

  • Project: microMIG: searching for new biomarkers in migraine using microRNA expression profile analysis
  • Principal Investigator: Patricia Vall, Pozo-Rosich, d’Hebron University Hospital

2014

Direct Grant – $190,000

  • Project: Patterns of Migraine Disease in Otolaryngology: A CHEER Network Study
  • Principal Investigator: David Witsell, MD, MHS, Duke University

MRF Grant – $50,000

  • Project: Gastroparesis in Monogenic Migraine Mouse Models
  • Principal Investigator: Robert Shapiro, UVM

MRF Grant – $50,000

  • Project: Use of Next Generation Sequencing Technology to Identify Novel Hemiplegic Migraine and Migraine Related Mutations.
  • Principal Investigator: Lyn Griffiths Ph.D., Queensland University of Technology

Direct Grant – $50,000

  • Project: The Role of Metabotropic Glutamate Receptors in Migraine
  • Principal Investigator: Maggie Waung, University of California San Francisco

Direct Grant – $50,000

  • Project: A prospective randomized cross-over trial of nortriptyline and topiramate in the initial treatment of vestibular migraine
  • Principal Investigator: Anthony Mikulec, MD, Saint Louis University