Parkinson’s Disease is a neurodegenerative disorder where nerve cells die in a part of the brain known as the substantia nigra. These nerve cells produce a neurotransmitter called dopamine. When the nerve cells die, dopamine production is decreased. The reduction of dopamine causes abnormal motor symptoms such as tremors, stiff muscles, coordination problems and slow movement but can also cause non-motor issues such as sleep problems, constipation, pain, urinary problems and more.
A study assessing the prevalence of migraine in 237 Parkinson’s Disease subjects found that 27.8% had migraine within their lifetime.1 In addition, after the onset of Parkinson’s Disease, two thirds had improvement in their migraine attacks or complete remission.1