Alice-in-Wonderland Syndrome is a rare neurological condition that can temporarily cause changes in visual perception, an altered sense of time as well as sensory and hearing abnormalities. When occurring comorbidly with migraine, the condition typically begins in childhood prior to the diagnosis of migraine. A migraine attack may occur before or after the Alice-in-Wonderland symptoms occur. This condition may be related to migraine with aura.
Clinical studies indicate about 15% of patients with migraine may also have the syndrome.1,2